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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP21 All Species: 17.88
Human Site: Y375 Identified Species: 65.56
UniProt: Q5T5U3 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T5U3 NP_065875.3 1957 217331 Y375 P S V S V N H Y S P N S H Q H
Chimpanzee Pan troglodytes XP_507699 1957 217438 Y375 P S V S V N H Y S P N S H Q H
Rhesus Macaque Macaca mulatta XP_001100413 1957 217419 Y375 P S V S V N H Y S P N S H Q H
Dog Lupus familis XP_548158 1061 116725
Cat Felis silvestris
Mouse Mus musculus Q6DFV3 1944 215724 Y370 P P V S V N H Y S A N S H Q H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506140 1948 216249 Y373 P S V A T N H Y S P N S H Q H
Chicken Gallus gallus
Frog Xenopus laevis Q6DFG0 1926 214694 S369 S P T N H Y S S P G P H Q Q I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.2 27.3 N.A. 86 N.A. N.A. 77 N.A. 62.3 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 99 35.6 N.A. 90.5 N.A. N.A. 84.8 N.A. 74.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 86.6 N.A. N.A. 86.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 86.6 N.A. N.A. 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 0 0 0 0 15 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % G
% His: 0 0 0 0 15 0 72 0 0 0 0 15 72 0 72 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 72 0 0 0 0 72 0 0 0 0 % N
% Pro: 72 29 0 0 0 0 0 0 15 58 15 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 15 86 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 58 0 58 0 0 15 15 72 0 0 72 0 0 0 % S
% Thr: 0 0 15 0 15 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 72 0 58 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _